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Symbol Name ID |
Isl1
ISL1 transcription factor, LIM/homeodomain MGI:101791 |
| Darker colors indicate more annotations |
| Human Phenotypes | Stroke |
Polydipsia |
Polyphagia |
Intellectual disability, mild |
| Disease(s) Associated with ISL1 | ||||
| atrial heart septal defect | ||||
| double outlet right ventricle | ||||
| type 1 diabetes mellitus |
| Mouse Phenotypes | decreased embryonic neuroepithelium thickness |
abnormal Rathke's pouch development |
small Rathke's pouch |
abnormal optic tract morphology |
abnormal optic nerve innervation |
abnormal motor neuron morphology |
decreased amacrine cell number |
decreased retina ganglion cell number |
abnormal sensory neuron morphology |
abnormal retina bipolar cell morphology |
abnormal retina ganglion cell morphology |
retina ganglion cell degeneration |
abnormal spinal cord interneuron morphology |
abnormal optic nerve morphology |
optic nerve degeneration |
optic nerve hypoplasia |
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| Availability | Mouse Genotype | ||||||||||||||||
| Isl1tm1Tmj/Isl1tm1Tmj | |||||||||||||||||
| Isl1tm1.1Whk/Isl1tm1.1Whk Tg(Six3-cre)69Frty/0 (conditional) |
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| Isl1tm2Gan/Isl1tm2Gan Tg(Six3-cre)69Frty/? (conditional) |
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| Isl1tm1(cre/Esr1*)Krc/Isl1tm2Sev (conditional) | |||||||||||||||||
| Isl1tm1Gan/Isl1tm2Gan Tg(Six3-cre)69Frty/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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